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Awards and Publications:

Recent awards and honor to the group members:

   Dr. Chau-Hwang Lee, 2012 Junior Research Investigators Award, Academia Sinica, Taiwan.

   Yu-Chiu Kao, 2011 Excellent Master Thesis Award by the Chinese Physical Society R.O.C. 

 

Highly Cited Papers (>= 25 citations)

  1. C.-H. Lee, W.-C. Lin, and J. Wang, “All-optical measurements of the bending rigidity of lipid-vesicle membranes across structural phase transitions,” Physical Review E 64, 020901(R) (2001).

  2. C.-H. Lee and J. Wang, “Noninterferometric differential confocal microscopy with 2-nm depth resolution,” Optics Communications 135, 233 (1997).

  3. T.-Y. Chien, C.-L. Chang, C.-H. Lee, J.-Y. Lin, J. Wang, and S.-Y. Chen, “Spatially localized self-injection of electrons in a self-modulated laser wakefield accelerator by using a laser-induced transient density ramp,” Physical Review Letters 94, 115003 (2005).

  4. H.-H. Chu, S.-Y. Huang, L.-S. Yang, T.-Y. Chien, Y.-F. Xiao, J.-Y. Lin, C.-H. Lee, S.-Y. Chen, and J. Wang, “A versatile 10-TW laser system with robust passive controls to achieve high stability and spatiotemporal quality,” Applied Physics B 79, 193 (2004).

  5. C.-H. Lee, H.-Y. Mong, and W.-C. Lin, “Noninterferometric wide-field optical profilometry with nanometer depth resolution,” Optics Letters 27, 1773 (2002).

  6. C.-H. Lee, C.-L. Guo, and J. Wang, “Optical measurement of the viscoelastic and biochemical responses of living cells to mechanical perturbation,” Optics Letters 23, 307 (1998).

  7. C.-H. Pai, S.-Y. Huang, C.-C. Kuo, M.-W. Lin, J. Wang, S.-Y. Chen, C.-H. Lee, and J.-Y. Lin, “Fabrication of spatial transient-density structures as high-field plasma photonic devices,” Physics of Plasmas 12, 070707 (2005).

  8. Y.-F. Xiao, H.-H. Chu, H.-E. Tsai, C.-H. Lee, J.-Y. Lin, J. Wang, and S.-Y. Chen, “Efficient generation of extended plasma waveguides with the axicon ignitor-heater scheme,” Physics of Plasmas 11, L21 (2004).

  9. H.-H. Chu, H.-E. Tsai, M.-C. Chou, L.-S. Yang, J.-Y. Lin, C.-H. Lee, J. Wang, and S.-Y. Chen, “Collisional-excitation soft x-ray laser pumped by optical-field ionization in a cluster jet,” Physical Review A 71, 061804(R) (2005).

  10. S.-H. Pan, Y.-C. Chao, P.-F. Hung, H.-Y. Chen, S.-C. Yang, Y.-L. Chang, C.-T. Wu, C.-C. Chang, W.-L. Wang, W.-K. Chan, Y.-Y. Wu, T.-F. Che, L.-K. Wang, C.-Y. Lin, Y.-C. Lee, M.-L. Kuo, C.-H. Lee, J. J. W. Chen, T.-M. Hong, and P.-C. Yang, “The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1,” Journal of Clinical Investigation 121, 3189 (2011).

  11. Y.-F. Chang, Q.-R. Chou, J.-Y. Lin, and C.-H. Lee, “Fabrication of high-aspect-ratio silicon nanopillar arrays with the conventional reactive ion etching technique,” Applied Physics A 86, 193 (2007).

  12. T.-H. Hsu, J.-L. Xiao, Y.-W. Tsao, Y.-L. Kao, S.-H. Huang, W.-Y. Liao, and C.-H. Lee, “Analysis of the paracrine loop between cancer cells and fibroblasts using a microfluidic chip,” Lab on a Chip 11, 1808 (2011).

  13. C.-C. Wang, Y.-C. Kao, P.-Y. Chi, C.-W. Huang, J.-Y. Lin, C.-F. Chou, J.-Y. Cheng, and C.-H. Lee, “Asymmetric cancer-cell filopodium growth induced by electric-fields in a microfluidic culture chip,” Lab on a Chip 11, 695 (2011).

  14. H.-Y. Hsieh, J.-L. Xiao, C.-H. Lee, T.-W. Huang, C.-S. Yang, P.-C. Wang, and F.-G. Tseng, “Au-coated polystyrene nanoparticles with HAR nanocorrugations via surface carboxylation shielded anisotropic etching for significant SERS signal enhancement,” Journal of Physical Chemistry C 115, 16258 (2011).

  15. B. Patra, Y.-H. Chen, C.-C. Peng, S.-C. Lin, C.-H. Lee, and Y.-C. Tung, “A microfluidic device for uniform-sized cell spheroids formation, culture, harvesting and flow cytometry analysis,” Biomicrofluidics 7, 054114 (2013).

 

                       The h-index of Dr. Chau-Hwang Lee's publications = 21.

 

 

 

Publications (PDF files of the reprints may be requested via e-mail.)

Cell activities in microenvironments


  1. B.-M. Chen, M. A. Al-Aghbar, C.-H. Lee, T.-C. Chang, Y.-C. Su, Y.-C. Li, S.-E. Chang, C.-C. Chen, T.-H. Chung, Y.-J. Liao, C.-H. Lee, and S. Roffler, “The affinity of elongated membrane-tethered ligands determines potency of T cell receptor triggering,” Frontiers in Immunology 8, 793 (2017).

  2. Y.-C. Kao, J.-R. Jheng, H.-J. Pan, W.-Y. Liao, C.-H. Lee, and P.-L. Kuo, “Elevated hydrostatic pressure enhances the motility and enlarges the size of the lung cancer cells through aquaporin upregulation mediated by caveolin-1 and ERK1/2 signaling,” Oncogene 36, 863 (2017).

  3. B. Patra, C.-C. Peng, W.-H. Liao, C.-H. Lee, and Y.-C. Tung, “Drug testing and flow cytometry analysis on a large number of uniform sized tumor spheroids using a microfluidic device,” Scientific Reports 6, 21061 (2016).

  4. Y.-H. Su, P.-C. Chiang, L.-J. Cheng, C.-H. Lee, N. S. Swami, and C.-F. Chou, “High aspect ratio nanoimprinted grooves of poly(lactic-co-glycolic acid) control the length and direction of retraction fibers during fibroblast cell division,” Biointerphases 10, 041008 (2015).

  5. C.-C. Lan, E. Y. Lu, H.-J. Pan, and C.-H. Lee, “Directional migration of cancer cells induced by a blue light intensity gradient,” Biomedical Optics Express 6, 2624 (2015).

  6. Y.-F. Hsiao, H.-J. Pan, Y.-C. Tung, C.-C. Chen, and C.-H. Lee, “Effects of hydraulic pressures on cardiomyoblasts in a microfluidic device,” Biomicrofluidics 9, 024111 (2015).

  7. B. Patra, Y.-S. Peng, C.-C. Peng, W.-H. Liao, Y.-A. Chen, K.-H. Lin, Y.-C. Tung, and C.-H. Lee, “Migration and vascular lumen formation of endothelial cells in cancer cell spheroids of various sizes,” Biomicrofluidics 8, 052109 (2014).

  8. Y.-C. Kao, M.-H. Hsieh, C.-C. Liu, H.-J. Pan, W.-Y. Liao, J.-Y. Cheng, P.-L. Kuo, and C.-H. Lee, “Modulating chemotaxis of lung cancer cells by using electric fields in a microfluidic device,” Biomicrofluidics 8, 024107 (2014).

  9. Y.-R. Liou, W. Torng, Y.-C. Kao, K.-B. Sung, C.-H. Lee, and P.-L. Kuo, “Substrate stiffness regulates filopodial activities in lung cancer cells,” PLoS ONE 9, e89767 (2014). 

  10. B. Patra, Y.-H. Chen, C.-C. Peng, S.-C. Lin, C.-H. Lee, and Y.-C. Tung, “A microfluidic device for uniform-sized cell spheroids formation, culture, harvesting and flow cytometry analysis,” Biomicrofluidics 7, 054114 (2013).

  11. H.-F. Tsai, C.-W. Huang, H.-F. Chang, J. J. W. Chen, C.-H. Lee, and J.-Y. Cheng, “Evaluation of EGFR and RTK signaling in the electrotaxis of lung adenocarcinoma cells under direct-current electric-field stimulation,” PLoS ONE 8, e73418 (2013).

  12. J.-L. Xiao, D.-H. Lu, and C.-H. Lee, “Guiding the migration of adherent cells by using optical micropatterns,” Applied Physics Letters 102, 123703 (2013).

  13. J.-W. Huang, H.-J. Pan, W.-Y. Yao, Y.-W. Tsao, W.-Y. Liao, C.-W. Wu, Y.-C. Tung, and C.-H. Lee, “Interaction between lung cancer cell and myofibroblast influenced by cyclic tensile strain,” Lab on a Chip 13, 1114 (2013).

  14. J.-L. Xiao, H.-J. Pan, and C.-H. Lee, “Optically micropatterned culture of adherent cells,” Journal of Biomedical Optics 17, 075004 (2012).

  15. T.-H. Hsu, Y.-L. Kao, W.-L. Lin, J.-L. Xiao, P.-L. Kuo, C.-W. Wu, W.-Y. Liao, and C.-H. Lee, “Migration speed of cancer cells influenced by macrophages and myofibroblasts co-cultured in a microfluidic chip,” Integrative Biology 4, 177 (2012).

  16. T.-H. Hsu, J.-L. Xiao, Y.-W. Tsao, Y.-L. Kao, S.-H. Huang, W.-Y. Liao, and C.-H. Lee, “Analysis of the paracrine loop between cancer cells and fibroblasts using a microfluidic chip,” Lab on a Chip 11, 1808 (2011).

  17. C.-C. Wang, Y.-C. Kao, P.-Y. Chi, C.-W. Huang, J.-Y. Lin, C.-F. Chou, J.-Y. Cheng, and C.-H. Lee, “Asymmetric cancer-cell filopodium growth induced by electric-fields in a microfluidic culture chip,” Lab on a Chip 11, 695 (2011).

  18. J.-L. Xiao, T.-H. Hsu, P.-Y. Hsu, W.-J. Yang, P.-L. Kuo, and C.-H. Lee, “Motion of cancer-cell lamellipodia perturbed by laser light of two wavelengths,” Applied Physics Letters 97, 203702 (2010).

 

 

Differential Confocal Microscopy, Wide-field Optical Profilometry, Super-resolution Bright-field Optical Microscopy, and their Applications in Biophysics and Cell Biology

 

  1. C.-H. Chang, H.-H. Lee, and C.-H. Lee, “Substrate properties modulate cell membrane roughness by way of actin filaments,” Scientific Reports 7, 9068 (2017).

  2. C.-W. Lee, C.-C. Wang, and C.-H. Lee, “Mechanoprofiling on membranes of living cells with atomic force microscopy and optical nano-profilometry,” Advances in Physics: X 2, 608 (2017).

  3. L. K. Chin, C.-H. Lee, and B.-C. Chen, “Imaging live cells at high spatiotemporal resolution for lab-on-a-chip applications,” Lab on a Chip 16, 2014 (2016).

  4. P. Y. Liu, L. K. Chin, W. Ser, H. F. Chen, C.-M. Hsieh, C.-H. Lee, K.-B. Sung, T. C. Ayi, P. H. Yap, B. Liedberg, K. Wang, T. Bourouinaj, and Y. Leprince-Wang, 2016, “Cell refractive index for cell biology and disease diagnosis: past, present and future,” Lab on a Chip 16, 634 (2016).

  5. C.-W. Lee, L.-L. Jang, H.-J. Pan, Y.-R. Chen, C.-C. Chen, and C.-H. Lee, “Membrane roughness as a sensitive parameter reflecting the status of neuronal cells in response to chemical and nanoparticle treatments,” Journal of Nanobiotechnology 14, 9 (2016).

  6. W.-Y. Liao, C.-C. Ho, H.-H. Hou, T.-H. Hsu, M.-F. Tsai, K.-Y. Chen, H.-Y. Chen, Y.-C. Lee, C.-J. Yu, C.-H. Lee, and P.-C. Yang, “Heparin cofactor II enhances cell motility and promotes metastasis in non-small-cell lung cancer,” Journal of Pathology 235, 50 (2015).

  7. L.-W. Chu, Y.-L. Huang, J.-H. Lee, L.-Y. Huang, W.-J. Chen, Y.-H. Lin, J.-Y. Chen, R. Xiang, C.-H. Lee, and Y.-H. Ping, “A single-virus tracking approach to reveal the interaction of Dengue virus with autophagy during the early stage of infection,” Journal of Biomedical Optics 19, 011018 (2014).

  8. H.-J. Pan, R.-L. Wang, J.-L. Xiao, Y.-J. Chang, J.-Y. Cheng, Y.-R. Chen, and C.-H. Lee, “Using optical profilometry to characterize cell membrane roughness influenced by amyloid-beta 42 aggregates and electric fields,” Journal of Biomedical Optics 19, 011009 (2014).

  9. S.-H. Pan, Y.-C. Chao, P.-F. Hung, H.-Y. Chen, S.-C. Yang, Y.-L. Chang, C.-T. Wu, C.-C. Chang, W.-L. Wang, W.-K. Chan, Y.-Y. Wu, T.-F. Che, L.-K. Wang, C.-Y. Lin, Y.-C. Lee, M.-L. Kuo, C.-H. Lee, J. J. W. Chen, T.-M. Hong, and P.-C. Yang, “The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1,” Journal of Clinical Investigation 121, 3189 (2011).

  10. T.-H. Liu, J.-L. Xiao, C.-H. Lee, and J.-Y. Lin, “Measurement of membrane rigidity on trapped unilamellar phospholipid vesicles by using differential confocal microscopy,” Applied Optics 50, 3311 (2011).

  11. F.-C. Tsai, L.-A. Tai, Y.-J. Wang, J.-L. Xiao, T.-H. Hsu, C.-S. Yang, and C.-H. Lee, “Three-dimensional tracking and temporal analysis of liposomal transport in live cells using bright-field imaging,” Microscopy Research and Technique 74, 531 (2011).

  12. Chien-Hong Chen, Feng-Ching Tsai, Chun-Chieh Wang, and Chau-Hwang Lee, “Three-dimensional characterization of active membrane waves on living cells,” Physical Review Letters 103, 238101 (2009).

  13. Chun-Chieh Wang, Chia-Pin Liang, and Chau-Hwang Lee, “Three-dimensional nanoparticle tracking and simultaneously membrane profiling during endocytosis of living cells,” Applied Physics Letters 95, 203702 (2009).

  14. Chun-Chieh Wang, Kuang-Li Lee, and Chau-Hwang Lee, “Wide-field optical nano-profilometry using structured illumination,” Optics Letters 34, 3538 (2009).

  15. T.-H. Hsu, M.-H. Yen, W.-Y. Liao, J.-Y. Cheng, and C.-H. Lee, “Label-free quantification of asymmetric cancer-cell filopodium activities in a multi-gradient chip,” Lab on a Chip 9, 884 (2009).

  16. Jiunn-Yuan Lin, Ru-Ping Huang, Pei-Shui Tsai, and Chau-Hwang Lee, “Wide-field super-resolution optical sectioning microscopy using a single spatial light modulator,” Journal of Optics A: Pure and Applied Optics 11, 015301 (2009).

  17. Chun-Chieh Wang, Hung-Jhang Jian, Chih-Wei Wu, and Chau-Hwang Lee, “Cell membrane deformations under magnetic force modulation characterized by optical tracking and profilometry,” Microscopy Research and Technique 71, 594 (2008).

  18. C.-C. Wang, C.-W. Lee, C.-Y. Huang, J.-Y. Lin, P.-K. Wei, and C.-H. Lee, “Internalization of nanoparticles on cell membranes observed by non-interferometric wide-field optical profilometry,” Applied Optics 47, 2458 (2008).

  19. Chun-Chieh Wang, Jiunn-Yuan Lin, Hung-Jhang Jian, and Chau-Hwang Lee, “Transparent thin-film characterization by using differential optical sectioning interference microscopy,” Applied Optics 46, 7460 (2007).

  20. T.-H. Hsu, W.-Y. Liao, P.-C. Yang, C.-C. Wang, J.-L. Xiao, and C.-H. Lee, “Dynamics of cancer cell filopodia characterized by super-resolution bright-field optical microscopy,” Optics Express 15, 76 (2007).

  21. Chun-Chieh Wang, Jiunn-Yuan Lin, Hsiao-Chao Chen, and Chau-Hwang Lee, “Dynamics of cell membranes and the underlying cytoskeletons observed by non-interferometric wide-field optical profilometry and fluorescence microscopy,” Optics Letters 31, 2873 (2006).

  22. Chun-Chieh Wang, Junn-Yuan Lin, and Chau-Hwang Lee, “Membrane ripples of a living cell measured by non-interferometric wide-field optical profilometry,” Optics Express 13, 10665 (2005).

  23. Chau-Hwang Lee, Yu-Fen Chang, Chia-Hsuan Tsai, and Po-Hsiang Wang, “Optical measurement of the deformation of giant lipid vesicles driven by a micropipette electrode,” Langmuir 21, 7186 (2005).

  24. Shu-Wei Huang, Hong-Yao Mong, and Chau-Hwang Lee, “Super-resolution bright-field optical microscopy based on nanometer topographic contrast,” Microscopy Research and Technique 65, 180 (2004).

  25. Chau-Hwang Lee, Hui-Yu Chiang, and Hong-Yao Mong, “Sub-diffraction-limit imaging based on the topographic contrast of differential confocal microscopy,” Optics Letters 28, 1772 (2003).

  26. Chau-Hwang Lee, Hong-Yao Mong, and Wan-Chen Lin, “Noninterferometric wide-field optical profilometry with nanometer depth resolution,” Optics Letters 27, 1773 (2002).

  27. Chau-Hwang Lee, Wan-Chen Lin, and Jyhpyng Wang, “All-optical measurements of the bending rigidity of lipid-vesicle membranes across structural phase transitions,” Physical Review E 64, 020901(R) (2001).

  28. Chau-Hwang Lee, Wan-Chen Lin, and Jyhpyng Wang, “Using differential confocal microscopy to detect the phase transition of lipid vesicle membranes,” Optical Engineering 40, 2077 (2001).

  29. Chao-Wei Tsai, Chau-Hwang Lee, and Jyhpyng Wang, “Deconvolution of local surface response from topography in nanometer profilometry with a dual-scan method,” Optics Letters 24, 1732 (1999).

  30. Chau-Hwang Lee, Chinlin Guo, and Jyhpyng Wang, “Optical measurement of the viscoelastic and biochemical responses of living cells to mechanical perturbation,” Optics Letters 23, 307 (1998).

  31. Chau-Hwang Lee and Jyhpyng Wang, “Noninterferometric differential confocal microscopy with 2-nm depth resolution,” Optics Communications 135, 233 (1997).

 

 
  • Patents:
  1. Optical Profilometry. US Patent 8,705,043 (2014/04/22), ROC (Taiwan) Patent I438392 (2014/05/21).

  2. Optical Sectioning Microscopy. US Patent 8,019,136 (2011/09/13), Japan Patent 5085608 (2012/09/05), ROC (Taiwan) Patent I414818 (2013/11/11).

  3. Modulation Differential Confocal Microscopy. ROC (Taiwan) Patent I329207 (2010/08/21).

  4. Method of Characterizing Transparent Thin-films Using Differential Optical Sectioning Interference Microscopy. US Patent 7,545,510 (2009/06/09), ROC (Taiwan) Patent I328676 (2010/08/11).

  5. Differential Confocal Microscopy. ROC (Taiwan) Patent 082212 (1996/11/01), US Patent 5,804,813 (1998/09/08).

 

Ultrafast Laser Technology and EUV Light Sources

  1. M.-C. Chou, P.-H. Lin, H.-E. Tsai, D.-L. Chen, C.-H. Lee, J.-Y. Lin, J. Wang, and S.-Y. Chen, “Characterization and control of plasma density distribution for development of solid-target x-ray lasers,” Physical Review E 72, 026401 (2005).

  2. C.-H. Pai, S.-Y. Huang, C.-C. Kuo, M.-W. Lin, J. Wang, S.-Y. Chen, C.-H. Lee, and J.-Y. Lin, “Fabrication of spatial transient-density structures as high-field plasma photonic devices,” Physics of Plasmas 12, 070707 (2005).

  3. H.-H. Chu, H.-E. Tsai, M.-C. Chou, L.-S. Yang, J.-Y. Lin, C.-H. Lee, J. Wang, and S.-Y. Chen, “Collisional-excitation soft x-ray laser pumped by optical-field ionization in a cluster jet,” Physical Review A 71, 061804(R) (2005).

  4. T.-Y. Chien, C.-L. Chang, C.-H. Lee, J.-Y. Lin, J. Wang, and S.-Y. Chen, “Spatially localized self-injection of electrons in a self-modulated laser wakefield accelerator by using a laser-induced transient density ramp,” Physical Review Letters 94, 115003 (2005).

  5. H.-H. Chu, S.-Y. Huang, L.-S. Yang, T.-Y. Chien, Y.-F. Xiao, J.-Y. Lin, C.-H. Lee, S.-Y. Chen, and J. Wang, “A versatile 10-TW laser system with robust passive controls to achieve high stability and spatiotemporal quality,” Applied Physics B 79, 193 (2004).

  6. Y.-F. Xiao, H.-H. Chu, H.-E. Tsai, C.-H. Lee, J.-Y. Lin, J. Wang, and S.-Y. Chen, “Efficient generation of extended plasma waveguides with the axicon ignitor-heater scheme,” Physics of Plasmas 11, L21 (2004).

  7. H.-H. Chu, H.-E. Tsai, Y.-F. Xiao, C.-H. Lee, J.-Y. Lin, J. Wang, and S.-Y. Chen, “Control of laser beam propagation and absorption in a nanoplasma gas by programming of transient complex refractive index with a prepulse,” Physical Review E 69, 035403(R) (2004).

  8. W.-T. Chen, T.-Y. Chien, C.-H. Lee, J.-Y. Lin, J. Wang, and S.-Y. Chen, “Optically controlled seeding of Raman forward scattering and injection of electrons in a self-modulated laser wakefield accelerator,” Physical Review Letters 92, 075003 (2004).

  9. T.-Y. Chien, W.-T. Chen, Y.-H. Chen, C.-H. Lee, J.-Y. Lin, J. Wang, and S.-Y. Chen, “Prepulse controlled splitting of relativistically self-guided channel and suppression of Raman forward scattering instability,” Physics of Plasmas 11, 1173 (2004).

  10. J.-Y. Lin, H.-H. Chu, M.-Y. Shen, Y.-F. Xiao, C.-H. Lee, S.-Y. Chen, and J. Wang, “High-brightness soft x-ray generation under optimized laser-cluster interaction,” Optics Communications 231, 375 (2004).

  11. T.-W. Yau, C.-J. Hsu, H.-H. Chu, Y.-H. Chen, C.-H. Lee, J. Wang, and S.-Y. Chen, “Dependence of relativistic self-guiding and Raman forward scattering on duration and chirp of an intense laser pulse propagating in a plasma,” Physics of Plasmas 9, 391 (2002).

  12. Tai-Wei Yau, Chau-Hwang Lee, and Jyhpyng Wang, “Femtosecond self-focusing dynamics measured by three-dimensional phase-retrieval cross correlation,” Journal of the Optical Society of America B 17, 1626 (2000).

  13. Tai-Wei Yau, Chau-Hwang Lee, and Jyhpyng Wang, “Spatial-temporal field distribution of self-focused femtosecond pulses,” Ultrafast Phenomena XI, edited by T. Elsaesser, et al. (Springer-Verlag, Berlin, 1998), pp. 106–108.

  14. Yi-Yuh Hwang, Chau-Hwang Lee, and Jyhpyng Wang, “Dynamic model of multipass ultrashort-pulse laser amplifiers and its application,” Applied Optics 36, 7802 (1997).

  15. Chau-Hwang Lee, Jyhpyng Wang, and Yuh-Fwu Chou, “Femtosecond transform-limited Kerr-lens mode-locked dye lasers,” Optical and Quantum Electronics 28, 1443 (1996).

  16. Yuh-Fwu Chou, Chau-Hwang Lee, and Jyhpyng Wang, “Characteristics of a femtosecond transform-limited Kerr-lens mode-locked dye laser,” Optics Letters 19, 975 (1994).

 

 

Micro/Nano Fabrications

  1. H.-Y. Hsieh, T.-W. Huang, J.-L. Xiao, C.-S. Yang, C.-C. Chang, C.-C. Chu, L.-W. Lo, S.-H. Wang, P.-C. Wang, C.-C. Chieng, C.-H. Lee, and F.-G. Tseng, “Fabrication and modification of dual-faced nano-mushrooms for tri-functional cell theranostics: SERS/fluorescence signaling, protein targeting, and drug delivering,” Journal of Materials Chemistry 22, 20918 (2012).

  2. H.-Y. Hsieh, J.-L. Xiao, C.-H. Lee, T.-W. Huang, C.-S. Yang, P.-C. Wang, and F.-G. Tseng, “Au-coated polystyrene nanoparticles with HAR nanocorrugations via surface carboxylation shielded anisotropic etching for significant SERS signal enhancement,” Journal of Physical Chemistry C 115, 16258 (2011).

  3. Y.-F. Chang, Q.-R. Chou, J.-Y. Lin, and C.-H. Lee, “Fabrication of high-aspect-ratio silicon nanopillar arrays with the conventional reactive ion etching technique,” Applied Physics A 86, 193 (2007).

  4. C.-H. Lee, T.-W. Chang, K.-L. Lee, J.-Y. Lin, and J. Wang, “Fabricating high-aspect-ratio sub-diffraction-limit structures on silicon with two-photon photopolymerization and reactive ion etching,” Applied Physics A 79, 2027 (2004).

 

 

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