鄭郅言
應科中心副主任 研究員
Ji-Yen Cheng
(Page on Web of Science)
jychenggate.sinica.edu.tw
02-2787-3136
ID
D-7272-2011
鄭郅言
應科中心副主任
研究員
Research Interests
- Nucleic acid and protein biosensors
- Microfluidic device development and applications
- Cell-based microalalysis, electrotaxis
Education
- Ph.D. Chemistry Department, National Taiwan University, TAIWAN, 1998
- M.S. Chemistry Department, National Taiwan University, TAIWAN, 1992
- B.S. Chemistry Department, National Taiwan University, TAIWAN, 1990
Positions and Career
- Deputy Director, RCAS, Academia Sinica, Taiwan, 2023 ~
- Executive Officer of Thematic Center Bio & Medical Application, 2021-2022
- Executive Officer of the TCMES (Thematic Center of Mechanics and Engineering Sciences) 2015, Jan ~ 2020
- Research Fellow, RCAS, Academia Sinica, Taiwan, 2013, Sep ~
- Associate Research Fellow, RCAS, Academia Sinica, Taiwan, 2007, May -2013 Sep
- Assistant Research Fellow, RCAS, Academia Sinica, Taiwan, 2001-2007
- Postdoctoral Fellow, IBMS, Academia Sinica, Taiwan, 1998-2001
- Adjunct Professor, National Taiwan Ocean University
- Adjunct Professor, National Yang Ming Chiao Tung University
Honors and Awards
- Cell-based micro analysis: cell responses in weak DC EF, cell-cell interaction co-culture chip, cellular chemotaxis, electrotaxis and metastasis, affinity binding and separation.
- Microfluidic biochip and their applications in biosensing.
- Microarray technologies: flexible in- situ array synthesis, rapid hybridization, mRNA labeling chip, and portable DNA amplification chip.
Selected Publications
- Lai, Y.T., Wei, P.K., Kuo, C.Y. and Cheng, J.Y. (2023) Inference detection and classification of illicit drugs by a modest Raman spectrometer with a convolutional neural network analyzer. Sensor Actuat B-Chem , 375. ARTN 132923 10.1016/j.snb.2022.132923.
- Belkin, S. and Cheng, J.Y. (2023) Miniaturized bioluminescent wholecell sensor systems. Current Opinion in Biotechnology , 82. ARTN 102952 10.1016/j.copbio.2023.102952.
- Huang, W.-C., Wei, C.-D., Belkin, S., Hsieh, T.-H. and Cheng, J.-Y. (2022) Machine-learning assisted antibiotic detection and categorization using a bacterial sensor array. Sensors and Actuators B: Chemical, 355, 131257.
- Chien, T.Y., Marin-Benavides, R., Belkin, S. and Cheng, J.Y. (2022) Rapid printing of a Bacterial array for a Solid-Phase Assay (BacSPA) of heavy metal ions. Sensor Actuat B-Chem, 359.
- Chou, S.E., Lee, K.L., Wei, P.K. and Cheng, J.Y. (2021) Screening antimetastasis drugs by cell adhesion-induced color change in a biochip. Lab Chip, 21, 2955-2970.
- Chang, H.F., Chou, S.E. and Cheng, J.Y. (2021) Electric-Field-Induced Neural Precursor Cell Differentiation in Microfluidic Devices. Jove-J Vis Exp.
- Yeung, W.K., Li, H.-F., Chung, C.-L., Lee, K.-L., Wei, P.-K., Lin, H., Chen, H.-H. and Cheng, J.-Y. (2020) Promising urinary miRNA biomarkers t-SPR profiling for urothelial cell carcinoma. Sensors and Actuators B: Chemical, 322, 128605.
- Tsai, H.-F., Tsai, Y.-C., Yagur-Kroll, S., Palevsky, N., Belkin, S. and Cheng, J.-Y. (2015) Water pollutant monitoring by a whole cell array through lens-free detection on CCD. Lab Chip, 15, 1472-1480.
- Wang, C.-C., Ka, Y.-C., Chi, P.-Y., Huang, C.-W., Lin, J.-Y., Chou, C.-F., Cheng, J.-Y. and Lee, C.-H. (2011) Asymmetric cancer-cell filopodium growth induced by electric-fields in a microfluidic culture chip. Lab Chip, 11, 695-699.
- Hsu, T.-H., Yen, M.-H., Liao, W.-Y., Cheng, J.-Y. and Lee, C.-H. (2009) Label-free quantification of asymmetric cancer-cell filopodium activities in a multi-gradient chip. Lab Chip, 9, 884-890.
- Cheng, J.-Y., Yen, M.-H., Kuo, C.-T. and Young, T.-H. (2008) A transparent cell culture microchamber with variably controlled concentration gradient generator and flow field rectifier. Biomicrofluidics, 2, 024105.
- Wei, C.-W., Cheng, J.-Y., Huang, C.-T., Yen, M.-H. and Young, T.-H. (2005) Using a microfluidic device for 1 microliter DNA microarray hybridization in 500 seconds. Nucleic Acids Research Methods, 33, e78.