Narrative CV

董奕鍾博士現任中央研究院應用科學研究中心研究員，自2009年加入中央研究院起致力於跨領域生醫研究。在加入中央研究院應用科學研究中心之前，董博士於美國密西根大學安娜堡分校生物醫學工程學系擔任博士後研究員（2006–2009），並於2005年獲得該校機械工程博士學位。董博士的研究貢獻廣受國際肯定，榮獲多項學術殊榮，包括2020–2022年度全球前2%頂尖科學家（單年度影響力）、2018年科技部傑出年輕學者研究計畫、2016年中央研究院前瞻計畫，以及2014年科技部吳大猷紀念獎。此外，他於2016年獲選為英國皇家化學學會（Royal Society of Chemistry, RSC）分析領域前 10% 高被引作者。董博士的研究專注於微流體細胞培養與分析、生醫儀器開發、以及先進微/奈米製造技術以推動生醫科技創新。他亦與國內外頂尖醫院及機構，如美國俄亥俄州立大學及波士頓大學，建立合作夥伴關係，推動生醫研究發展。目前，其實驗室正積極研發自動化與智慧化生醫儀器，以提升生醫研究效能，特別聚焦於癌症與神經科學相關議題。

Education

• Ph. D. in Mechanical Engineering, University of Michigan, Ann Arbor (2005)
• M.S.E. in Electrical Engineering, University of Michigan, Ann Arbor (2004)
• M.S. in Mechanical Engineering, National Taiwan University (1998)
• B.S. in Mechanical Engineering, National Taiwan University (1996)

Positions and Career

• 中央研究院應用科學研究中心智慧生物工程專題中心 執行長 (2025 - )
• 中央研究院應用科學研究中心 研究員 (2018 - )
• 中央研究院應用科學研究中心 副研究員 (2013 - 2018)
• 中央研究院應用科學研究中心 助研究員 (2009 - 2013)
• 美國密西跟大學生醫工程學系 博士後研究員 (2006 - 2009)

Honors and Awards

• 2020-2022 Scientist with Top 2% Single Year Impact
• 2018 台灣科技部 優秀年輕學者研究計畫
• 2016 中央研究院 前瞻計畫
• 2016 Analytical Portfolio of Royal Society of Chemistry (RSC) Journals, Top 10% Highly Cited Author
• 2014 台灣科技部 吳大猷先生紀念獎

Selected Publications

• D.-M. Chang, H.-H. Hsu, P.-L. Ko, T.-H. Hsieh, H.-M. Wu*, and Y.-C. Tung*, "Rapid Time-Lapse 3D Oxygen Tension Measurement within Hydrogels Using Widefield Frequency Domain Fluorescence Lifetime Imaging Microscopy (FD-FLIM) and Image Segmentation," Analyst, Vol. 149, Issue 6, pp. 727-1737, March 2024. (Featured as the back cover image)
• H.-H. Hsu, P.-L. Ko, C.-C. Peng, Y.-J. Cheng, H.-M. Wu, and Y.-C. Tung*, "Studying Sprouting Angiogenesis under Combination of Oxygen Gradients and Co-Culture of Fibroblasts Using Microfluidic Cell Culture Model," Materials Today Bio, Vol. 21, 100703, August 2023.
• C.-W. Chang, H.-C. Shih, M. Cortes-Medina, P. E. Beshay, A. Avendano, A. J. Seibel, W.-H. Liao, Y-C. Tung*, and J. W. Song*, "ECM-Derived Biophysical Cues Mediate Interstitial Flow-Induced Sprouting Angiogenesis," ACS Applied Materials & Interfaces, Vol. 15, pp. 15047-15088, March 2023.
• P.-L. Ko, C.-K. Wang, H.-H. Hsu, T.-A. Lee, and Y.-C. Tung*, "Revealing Anisotropic Elasticity of Endothelium under Fluid Shear Stress," Acta Biomaterialia, Vol. 145, pp. 316-328, June 2022.
• Y.-C. Tung, C.-K. Wang, Y.-K. Huang, C.-K. Huang, C.-C. Peng, B. Patra, H.-K. Chen, P.-N. Tsao*, and T.-Y. Ling*, "Identifying Distinct Oxygen Diffusivity through Type I Pneumocyte-Like Cell Layers Using Microfluidic Device," Talanta, Vol. 236, 122882, January 2022.
• Y.-C. Chen, J.-J. Chen, Y.-J. Hsiao, C.-Z. Xie, C.-C. Peng, Y.-C. Tung*, and Y.-F. Chen*, "Plasmonic Gel Films for Time-Lapse LSPR Detection of Hydrogen Peroxide Secreted from Living Cells," Sensors and Actuators B: Chemical, Vol. 336, 129725, June 2021.
• H.-H. Hsu, P.-L. Ko, H.-M. Wu, H.-C. Line, C.-K. Wang, and Y.-C. Tung*, "Study Formation of Three-Dimensional Endothelial Cell Network under Various Oxygen Microenvironment and Hydrogel Composition Combinations Using Upside-Down Microfluidic Device," Small, Vol. 17, Issue 15, 2006091, April 2021. (Featured as the inside back cover image)
• H.-C. Shih, T.-A. Lee, H.-M. Wu, P.-L. Ko, W.-H. Liao, and Y.-C. Tung*, "Microfluidic Collective Cell Migration Assay for Study of Endothelial Cell Proliferation and Migration under Combinations of Oxygen Gradients, Tensions, and Drug Treatments," Scientific Reports, Vol. 9, 8234, June 2019.
• H.-M. Wu, T.-A. Lee, P.-L. Ko, W.-H. Liao, T.-H. Hsieh, and Y.-C. Tung*, "Widefield Frequency Domain Fluorescence Lifetime Imaging Microscopy (FD-FLIM) for Accurate Measurement of Oxygen Gradients within Microfluidic Devices," Analyst, Vol. 144, Issue 11, pp. 3494-3504, June 2019. (Featured as the inside back cover image)

• Y.-H. Liu, M.-T. Chung, H.-C. Lin, T.-A. Lee, Y.-J. Cheng, C.-C. Huang, H.-M. Wu*, and Y.-C. Tung*, “Shaping Early Neural Development by Timed Elevated Tissue Oxygen Tension: Insights from Multiomic Analysis on Human Cerebral Organoids,” Science Advances, Vol. 11, ado1164, March 2025.
• H.-H. Hsu, P.-L. Ko, C.-C. Peng, Y.-J. Cheng, H.-M. Wu, and Y.-C. Tung*, “Studying Sprouting Angiogenesis under Combination of Oxygen Gradients and Co-Culture of Fibroblasts Using Microfluidic Cell Culture Model,” Materials Today Bio, Vol. 21, 100703, August 2023.
• C.-W. Chang, H.-C. Shih, M. Cortes-Medina, P. E. Beshay, A. Avendano, A. J. Seibel, W.-H. Liao, Y.-C. Tung*, and J. W. Song*, “ECM-Derived Biophysical Cues Mediate Interstitial Flow-Induced Sprouting Angiogenesis,” ACS Applied Materials & Interfaces, Vol. 15, pp. 15047-15088, March 2023.
• P.-L. Ko, C.-K. Wang, H.-H. Hsu, T.-A. Lee, and Y.-C. Tung*, “Revealing Anisotropic Elasticity of Endothelium under Fluid Shear Stress,” Acta Biomaterialia, Vol. 145, pp. 316-328, June 2022.
• H.-H. Hsu, P.-L. Ko, H.-M. Wu, H.-C. Line, C.-K. Wang, and Y.-C. Tung*, “Study Formation of Three-Dimensional Endothelial Cell Network under Various Oxygen Microenvironment and Hydrogel Composition Combinations Using Upside-Down Microfluidic Device,” Small, Vol. 17, Issue 15, 2006091, April 2021. (Featured as the inside back cover image)